Author: Alexis Hughes

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Health Information

Understanding Myasthenia Gravis

Man with myasthenia gravis who's experiencing ptosis

Myasthenia gravis (MG) is a rare, chronic neuromuscular, autoimmune disorder that causes weakness in the skeletal muscles. It affects communication between the nerves and muscles, leading to muscle fatigue and weakness. In this guide, we will share information about what myasthenia gravis is, its causes, symptoms, how it’s diagnosed, and available treatments. 

 

What is Myasthenia Gravis? 

Myasthenia gravis is an autoimmune disorder in which the immune system mistakenly attacks the connections between nerve endings and muscle receptors, disrupting normal nerve-muscle communication. This leads to muscle weakness and fatigue. This weakness is often worse with activity and can improve with rest. The condition can affect a variety of muscles, impairing functions such as eye movement, facial expressions, mobility, movement, swallowing, and breathing. According to the Myasthenia Gravis Foundation of America, there are over 70,000 individuals living with myasthenia gravis in the United States. 

 

What Causes Myasthenia Gravis? 

Myasthenia gravis is an autoimmune disorder in which the immune system mistakenly targets and attacks itself. Although the exact cause of this abnormal response is not fully understood, it is thought to result from a disruption in the communication between nerves and muscles. While anyone can develop MG, it affects both men and women and occurs across all racial and ethnic groups. It most commonly impacts young adult women (under 40) and older men (over 60), however it can occur at any age, including childhood 

 

Myasthenia Gravis Symptoms 

The symptoms of myasthenia gravis can vary greatly depending on which muscles are affected. As a rare condition, it’s important to recognize the signs in order to advocate for appropriate care with your healthcare provider. Common symptoms include: 

  • Muscle Weakness: This often affects muscles that control eye movements, facial expressions, arm, hand, fingers, leg, and neck function.
  • Drooping Eyelids: Ptosis, or drooping of one or both eyelids, is often an early sign of MG. 
  • Blurry or Double Vision: Diplopia, or double vision, occurs due to weakness in the eye muscles. 
  • Changes in Facial Expressions: For example, a smile might look like a snarl. 
  • Difficulty Swallowing or Speaking: Weakness in the muscles responsible for swallowing and speech can result in choking or slurred speech. 
  • Difficulty Chewing: The muscles used for chewing might tire halfway through a meal. This is especially true if someone has been eating something hard to chew, such as steak. 
  • Trouble Breathing: In severe cases, MG can affect respiratory muscles, making breathing difficult. 

How to Diagnose Myasthenia Gravis 

Diagnosing myasthenia gravis involves a series of steps. If you experience muscle weakness or fatigue, a healthcare provider will assess your symptoms and medical history before conducting tests to confirm the diagnosis. Diagnostic procedures may include: 

  • Physical and Neurological Evaluation: Your healthcare provider will test your reflexes, muscle strength, coordination, and balance to assess your neurological health.  
  • Ice Pack Test: This test involves measuring the eyelid opening, placing an ice pack over the eye for 2–5 minutes, and then remeasuring the eyelid to see if there’s a noticeable improvement, which may indicate MG.  
  • Blood Antibody Tests: A blood test can identify abnormal antibodies that interfere with the communication between nerves and muscles, a common sign of MG.  
  • Imaging Scans: A CT scan of the chest is often performed for individuals with symptoms or a confirmed diagnosis to help detect thymoma, a tumor of the thymus gland that may be associated with MG.  
  • Electromyography (EMG): This test detects impaired nerve-to-muscle transmission. 
  • Repetitive nerve stimulation (RNS): This test repeatedly stimulates the nerves with small pulses of electricity and is used to assess muscle response. helping to determine if the muscle response is consistent with MG. 

Myasthenia Gravis Treatments 

While there is no cure for myasthenia gravis, several treatments are available to help manage symptoms and improve quality of life. These treatments include: 

  • Medications: Medications like pyridostigmine enhance nerve-to-muscle communication, while immunosuppressive drugs such as corticosteroids and azathioprine reduce harmful antibodies attacking muscle receptors.
  • Thymectomy: In some cases, surgical removal of the thymus gland may benefit individuals with MG, especially those with thymoma. This procedure has been shown to improve symptoms and reduce reliance on long-term medication in some people.
  • Immunoglobulin Therapy (Ig therapy): Intravenous immunoglobulin (IVIg) and subcutaneous immunoglobulin (SCIg) both work by increasing the levels of immunoglobulins in the blood. These treatments have multiple effects on the immune system, including reducing the abnormal antibodies that attack the acetylcholine receptors, which are responsible for the symptoms of myasthenia gravis. 

 

Living With Myasthenia Gravis: Support Resources 

While living with myasthenia gravis can be challenging, many individuals with MG lead fulfilling lives with the right medical care. Early diagnosis, regular monitoring, and proper treatments are key to reducing the risk of infections and improving quality of life. There are several resources and support organizations for individuals with myasthenia gravis including: 

Myasthenia Gravis Foundation of America (MGFA) 

MGFA is a non-profit organization dedicated to improving the diagnosis, treatment, and quality of life for individuals affected by myasthenia gravis. They provide valuable resources, education, and advocacy for patients and their families.  

IVIG & SCIG Support Community 

Founded by CSI Pharmacy, the IVIG & SCIG Support Community on Facebook is a group for individuals and caregivers of adults or children receiving IVIg or SCIg treatments. This community is designed to educate, empower, and support members on their journey. It’s a space for individuals impacted by rare and chronic diseases, including MG, to access resources, ask questions, share insights, and more.  

National Organization for Rare Diseases (NORD) 

NORD advances practical, meaningful, and enduring change so people with rare diseases can live their fullest and best lives. They offer disease information, community events and programs, and financial assistance programs for individuals with rare diseases, such as MG. 

 

In-Home IVIg & SCIg Treatments for Myasthenia Gravis 

Myasthenia gravis (MG) is a complex condition, but with the right treatments and support, individuals with MG can successfully manage their symptoms and enhance their quality of life. Access to in-home IVIg and SCIg treatments from CSI Pharmacy provides a convenient and effective treatment option. If you or a loved one is navigating this condition, consult with the CSI team to explore personalized treatment options and comprehensive support tailored to your needs.

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Health Information

Understanding Primary Immunodeficiency (PID)

Individual with Primary Immunodeficiency experiencing a sinus infection

Primary Immunodeficiency (PID or PI) is a rare, chronic condition where the immune system is either absent or functioning improperly. As a result, individuals with PID have a weakened immune system, making it difficult for their bodies to effectively fight off infections. This can lead to frequent illnesses and other medical complications. In this blog post, we’ll explore what Primary Immunodeficiency is, the causes, and the treatments available to manage these conditions. 

What is Primary Immunodeficiency? 

Primary Immunodeficiency (PID) is a condition that affects the immune system, leaving the body less able to defend itself against infections. PID is present from birth, but may not be diagnosed until adulthood, and is caused by genetic mutations that affect the immune system’s ability to function properly. 

There are over 400 types of primary immunodeficiency conditions, ranging from milder symptoms that are manageable to more severe cases that can significantly impact a person’s health and quality of life. Common signs and symptoms of PID include: 

  • Recurrent infections (sinus, ear, skin, or digestive)
  • Difficulty recovering from infections even with antibiotics
  • Poor growth and development in children
  • Delayed healing after injuries 

It is essential for individuals with PID to receive timely diagnosis and treatment to help manage the condition, reduce future complications due to recurrent infections, and improve quality of life. 

Causes of Primary Immunodeficiency 

Primary Immunodeficiency conditions are caused by genetic mutations that affect the immune system. These mutations can interfere with the production of immune cells or proteins that are vital for defending the body against infections. These mutations may be inherited or may occur in individuals with no family history of PID.  

There are different types of PID, each caused by mutations in specific genes. Some mutations may result in partial immune dysfunction, while others cause complete absence or malfunction of immune cells, making individuals highly susceptible to infections.  

Managing & Treating Primary Immunodeficiency  

Although Primary Immunodeficiency cannot be cured, effective management strategies are available to help individuals with PID live a healthier, more comfortable life. The treatment approach to PID depends on the type and severity of the condition. 

Treatment options for PID often include: 

  • Immunoglobulin Replacement Therapy: One of the most common treatments for individuals with PID is immunoglobulin replacement therapy (Ig therapy). This involves infusing healthy antibodies to strengthen the patient’s immune system. This can be administered as either Intravenous Immunoglobulin (IVIg) Therapy or Subcutaneous Immunoglobulin (SCIg) therapy.
  • Antibiotics: To help prevent or treat infections, individuals with PID may be prescribed long-term antibiotics. These antibiotics often provide much-needed support to the weakened immune system.
  • Bone Marrow Transplant: For individuals with severe types of PID, particularly when the disease poses significant risks to health or life, a bone marrow transplant (also known as allogeneic hematopoietic stem cell transplant or HSCT) may be considered. This procedure replaces defective immune cells with healthy ones from a donor, restoring immune function and potentially alleviating symptoms.
  • Gene Therapy: While gene therapy is not yet FDA-approved for treating PID, it is currently undergoing clinical trials as a promising alternative to bone marrow transplants. Gene therapy aims to offer a potential solution for patients who do not have a suitable donor for an HSCT. 

Living with Primary Immunodeficiency  

While living with Primary Immunodeficiency can be challenging, many individuals with PID lead fulfilling lives with the right medical care. Early diagnosis, regular monitoring, and proper treatments are key to reducing the risk of infections and improving quality of life. There are several resources and support organizations for individuals with PID including:

Immune Deficiency Foundation (IDF) 

Immune Deficiency Foundation is a non-profit organization dedicated to improving the diagnosis, treatment, and quality of life for individuals affected by Primary Immunodeficiency. They provide valuable resources, education, and advocacy for patients and their families. 

IVIG & SCIG Support Community 

Founded by CSI Pharmacy, the IVIG & SCIG Support Community on Facebook is a group for individuals and caregivers of adults or children receiving IVIg or SCIg treatments. This community is designed to educate, empower, and support members on their journey. It’s a space for individuals impacted by rare and chronic diseases, including PID, to access resources, ask questions, share insights, and more. 

National Organization for Rare Diseases (NORD) 

NORD advances practical, meaningful, and enduring change so people with rare diseases can live their fullest and best lives. They offer disease information, community events and programs, and financial assistance programs for individuals with rare diseases, such as PID. 

In-Home IVIg & SCIg Treatments for Primary Immunodeficiencies 

Primary Immunodeficiency (PID) is a complex condition, but with the right treatments and support, individuals with PID can successfully manage their symptoms and enhance their quality of life. Access to in-home IVIg and SCIg treatments from CSI Pharmacy provides a convenient and effective treatment option. If you or a loved one is navigating this condition, consult with the CSI team to explore personalized treatment options and comprehensive support tailored to your needs. 

References: 

Centers for Disease Control and Prevention.  www.CDC.gov . May 15, 2024 Primary immunodeficiency (PI). Retrieved February 12, 2025, from https://www.cdc.gov/primary-immunodeficiency/about/  

Immune Deficiency Foundation. Retrieved February 12, 2025, from https://primaryimmune.org/understanding-primary-immunodeficiency/treatment/gene-therapy 

Categories
IG Therapy Infusion

What to Know About Subcutaneous Immunoglobulin (SCIg)

Subcutaneous immunoglobulin (SCIg) therapy is a medical treatment used to manage rare and chronic primary immune deficiencies, certain autoimmune conditions, and some neurological disorders. SCIg provides patients with a vital source of antibodies to enhance their immune system’s ability to fight infections and maintain overall health. This article will explore the benefits of SCIg, uses, and administration process of SCIg to help patients, caregivers, and healthcare professionals understand its role in treating these conditions. 

 

What is Subcutaneous Immunoglobulin (SCIg)? 

SCIg is a form of immunoglobulin therapy in which purified antibodies are injected under the skin (subcutaneously) rather than into a vein. Immunoglobulins are essential proteins that help fight infections caused by bacteria and viruses. When the body can’t produce enough antibodies on its own, SCIg therapy provides them as replacement therapy to improve immune function. By delivering the necessary antibodies, SCIg helps patients fight infections more effectively and supports overall immune health. 

Administration of SCIg Treatments 

SCIg is administered through a subcutaneous injection, meaning immunoglobulin is injected beneath the skin rather than directly into a vein. These injections are typically given in the fatty tissue of the abdomen, thigh, or upper arm. After receiving proper training from an experienced infusion nurse, many patients are able to administer SCIg at home on their own. Each infusion typically requires 3-4 needles, depending on the dosage. Subcutaneous infusions can be scheduled in smaller doses a few times a week, or larger doses once a week or every other week, depending on the patient’s specific treatment plan. 

 

Diseases Treated with SCIg Therapy 

SCIg infusion is a potential treatment option for patients with immunodeficiencies, autoimmune diseases, and neurological conditions that affect the immune system, including: 

  • Primary Immunodeficiencies (PID) 
  • Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) 

 

Benefits of SCIg Therapy 

SCIg therapy offers a range of benefits for patients with rare and chronic health conditions, including: 

  • Immune Globulin Replacement: SCIg replaces the missing or dysfunctional antibodies in patients who have an immune deficiency. The goal of SCIg is to reduce the frequency, severity, and potential complications of repeated infections. 
  • Convenient Self Administration at Home: With proper training from an infusion nurse, many patients can conveniently administer SCIg therapy at home, reducing the need for frequent nurse visits. 
  • Minimal Side Effects: SCIg therapy usually causes fewer side effects that affect the whole body as compared to IVIg therapy. This can make it a comfortable option for long-term treatments. 
  • Improved Quality of Life: SCIg may allow patients to experience fewer infections, better immune health, and increased energy levels to improve their overall quality of life. 

 

SCIg Therapy Side Effects 

As with any medical treatment, SCIg treatments may come with some mild side effects. Common side effects include temporary pain, redness, or swelling at the injection site. Some patients may experience mild headaches or fatigue as well. Less common symptoms include fever or chills. It’s important to consult with a healthcare provider about any side effects or concerns to make sure they are managed with proper care. 

 

In-Home SCIg Therapy with CSI Pharmacy 

At CSI Pharmacy, we specialize in IVIg and SCIg infusion therapies for patients with immunodeficiencies, autoimmune, and other rare or chronic conditions. Our nationwide team of nurses is committed to delivering expert, compassionate care in the comfort of your home. Alongside our dedicated pharmacy, insurance & reimbursement, and intake teams, we ensure that you have the support you need every step of the way. If you’re looking for an IVIg or SCIg partner, let us help make the process seamless and stress-free. 

Categories
IG Therapy

What to Know About Intravenous Immunoglobulin (IVIg)

An infusion nurse giving a patient an IVIg infusion.

Intravenous Immunoglobulin (IVIg) therapy is a medical treatment used to manage a range of rare primary immune deficiencies, autoimmune conditions, and some neurological disorders. IVIg is made from pooled human plasma and contains antibodies that are vital for the immune system’s proper function. Review this guide on IVIg for a better understanding of how it works, the diseases it is used to treat, and more. 

 

How Does IVIg Work? 

IVIg therapy involves infusing immunoglobulins directly into the bloodstream. Immunoglobulins, also known as antibodies, are proteins that play a crucial role in defending the body against infections. When administered through an intravenous (IV) infusion, these antibodies help boost the immune system’s ability to fight off diseases and infections in patients who have an immune deficiency. 

Administration of IVIg Treatments 

IVIg therapy is generally administered by a medical professional in the comfort of the patient’s home or at a healthcare clinic/hospital. The infusion process generally takes a few hours, with the exact duration depending on the dosage and the patient’s specific condition. The frequency of treatments may vary, with some individuals receiving IVIg therapy once a month, while others may require more frequent infusions. 

 

Diseases Treated with IVIg Therapy 

IVIg therapy is a potential treatment option for patients with a variety of immunodeficiencies, autoimmune diseases, and neurological disorders that affect the immune system. Some of these conditions include: 

  • Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) 
  • Common Variable Immunodeficiency (CVID) 
  • Multifocal Motor Neuropathy (MMN) 
  • Multiple Sclerosis (MS) 
  • Myasthenia Gravis 
  • Myositis 
  • Pemphigus & Pemphigoid 

Benefits of IVIg Therapy 

IVIg therapy offers several benefits for individuals with chronic and rare medical conditions. Some key benefits of IVIg include: 

  1. Immune Globulin Replacement: IVIg replaces the missing or dysfunctional antibodies in patients who have an immune deficiency. The goal is to reduce the frequency, severity, and potential complications of repeated infections. 
  2. Immune Modulation: IVIg treatments may help reduce the body’s over-reactive response in autoimmune conditions and improve symptoms like pain, muscle weakness, and nerve damage. 
  3. Improved Quality of Life: By reducing the frequency and severity of symptoms, IVIg can significantly improve the quality of life for many individuals. 

 

IVIg Therapy Side Effects 

Like any medical treatment, IVIg treatments can cause side effects. However, they are generally mild and temporary. Common side effects include headache, fever, chills, fatigue, and nausea. In rare instances, individuals may experience allergic reactions, kidney problems, or blood clotting. It is important to discuss any concerns with your healthcare provider prior to starting treatments. Your infusion therapy provider should monitor your condition during and after treatments and manage any side effects that arise. 

 

In-Home IVIg Therapy with CSI Pharmacy 

In-home IVIg therapy provides patients with the convenience and comfort of receiving their infusions at home while maintaining the highest standards of care. CSI Pharmacy offers personalized, compassionate therapy, administered by skilled medical professionals to provide a safe and effective treatment experience in the comfort of your own home. Reach out to CSI Pharmacy today to learn more about how they can support your healthcare needs with in-home IVIg therapy. 

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IG Therapy

What to Look for in an IVIg and SCIg Therapy Provider

Caregiver giving an infusion to a senior woman

Choosing the right IVIg (Intravenous Immunoglobulin) or SCIg (Subcutaneous Immunoglobulin) therapy provider is crucial to ensure that you receive quality care and the best possible outcomes. If you or a loved one is considering IVIg or SCIg therapy, it’s important to find a trusted, reliable provider. In this guide, we’ll walk you through the key factors to consider when choosing an IVIg or SCIg therapy provider.

What Are IVIg and SCIg Therapies?

IVIg and SCIg therapies are complex treatments for patients with immune deficiencies and various autoimmune disorders. These infusion therapies utilize the administration of immunoglobulin (antibodies) to help strengthen the immune system to manage and treat chronic conditions.
Conditions treated with IVIg and SCIg:

  • Primary Immunodeficiencies
  • Myasthenia Gravis
  • Myositis
  • Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
  • Guillain-Barre Syndrome
  • Multiple Sclerosis

What to Consider When Choosing an Infusion Therapy Provider

Expertise in Immunoglobulin Therapies

When undergoing IVIg or SCIg treatment, it is important that your provider has specialized knowledge and experience in administering these therapies. Ensure your provider employs registered nurses and board-certified pharmacists who are experienced in managing immunoglobulin therapies for your condition. A great way to verify a provider’s expertise is by checking their IgNS (Immunoglobulin National Society) credentials. IgNS certification verifies that providers have undergone comprehensive training and demonstrated clinical competence in immunoglobulin therapy.

Personalized Treatment Plans

Every patient’s needs are unique, especially when it comes to immunoglobulin therapy. The dosage and frequency of treatments vary based on the condition and medical history. Make sure your provider offers personalized treatment plans, tailored to your individual needs, including customized dosing and ongoing assessments to monitor the success of the treatment to make adjustments when needed.

Comfort and Convenience

Since IVIg and SCIg treatments often require regular treatment sessions, sometimes taking place over several hours or multiple days, it’s important to prioritize comfort and convenience. Many patients benefit from home infusion services, where treatments are administered in the comfort of their own home. If in-home care is not an option for you, check if your provider offers flexible clinic or hospital settings that work with your schedule.

Safety Protocols and Monitoring

Safety is of utmost importance for the administration of immunoglobulin therapies. IVIg and SCIg treatments can cause side effects, so your provider must have safety protocols in place. Ensure your nurse monitors your response to the therapy and takes action if necessary. Your provider should regularly assess your progress through clinical assessments to ensure that your body is responding well to the treatment.

Insurance Coverage and Cost

Immunoglobulin therapy can be expensive, and the financial responsibility can vary depending on your insurance plan. Before choosing a provider, make sure you understand their insurance policies and payment options. Verify whether they accept your insurance and if they are in-network. Look for a provider who offers transparent pricing, including any out-of-pocket costs, copays, and potential financial assistance programs.

Patient Reviews and Reputation

One of the most effective ways to evaluate a potential IVIg or SCIg provider is by looking at patient reviews and feedback. Hearing about other patients’ experiences can provide valuable insights into the quality of care and overall patient satisfaction. Look for a provider with a strong reputation for compassionate care, clear communication, and positive treatment outcomes.

IVIg and SCIg Treatments with CSI Pharmacy

At CSI Pharmacy, we understand the importance of specialized, personalized care for patients receiving IVIg and SCIg therapies. We offer in-home infusion therapy and specialty pharmacy services with rare and chronic conditions. Our team of experienced, certified professionals are committed to patient comfort, safety, and support, ensuring patients receive the best possible care. Start your journey with the individualized care you deserve!

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Health Information

Understanding Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Trauma And Rheumatoid Arthritis Concept. Sad mature male holding touching his knee feeling acute pain, sick senior guy suffering from aching leg sitting on couch at home, selective focus on hand

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a rare neurological disorder that affects the peripheral nervous system, causing progressive weakness, sensory loss, and discomfort. Understanding CIDP, its symptoms, and available treatments essential for patients, caregivers, and healthcare providers. In this article, we’ll share information about CIDP, from diagnosis to treatment options.

What Is CIDP?

CIDP, Chronic Inflammatory Demyelinating Polyneuropathy, is an autoimmune disorder where the body’s immune system attacks the myelin sheaths that covers the nerves in the peripheral nervous system. This leads to muscle weakness, numbness, and difficulty walking. CIDP is often compared to Guillain-Barre syndrome (GBS), but CIDP progresses over a longer period, causing more gradual nerve damage than GBS. According to Cleveland Clinic, researchers estimate that there are 0.8 to 8.9 new cases of CIDP per 100,000 people in the United States each year.

Symptoms of CIDP

CIDP symptoms often vary by person and develop slowly, making detection challenging. Common symptoms of CIDP include:

  • Chronically Progressive Muscle Weakness: Muscle strength may gradually diminish over 2 months or longer, particularly in the legs and arms.
  • Sensory Disturbances: Individuals affected by CIDP may experience numbness or tingling.
  • Fatigue: Constant tiredness can make it difficult to complete daily activities.
  • Difficulty with Coordination: Walking and maintaining balance can become challenging for individuals with CIDP.
  • Neuropathic Pain: Nerve pain is common and can range from mild discomfort to intense burning or sharp sensations.

Diagnosing CIDP

Healthcare providers will utilize a combination of diagnostic methods to evaluate for CIDP including medical history review, physical exams, and diagnostic tests. Common tests for CIDP include nerve conduction studies, spinal tap (lumbar puncture), and blood tests. Early diagnosis and intervention can help to effectively manage the progression of the disease to improve the patient’s quality of life.

Treatment Options for CIDP

There is currently no cure for CIDP but several treatments help manage the symptoms. The most common treatment options include:

  • Corticosteroids: These prescription medications, such as prednisone, can help reduce inflammation.
  • Steroid-sparing Immunosuppressants: These prescription medications may include methotrexate, azathioprine, and mycophenolate.
  • Intravenous Immunoglobulin (IVIg): This infusion therapy helps regulate the immune system, promote nerve function recovery, and provide symptom relief to slow disease progression.

Resources for Individuals with CIDP & Caregivers

Support and education are important for individuals with CIDP and their caregivers. Several organizations offer valuable resources including education, community support, and even financial assistance. Some helpful organizations for individuals with CIDP include:

GBS | CIDP Foundation International
The GBS | CIDP Foundation International is a global nonprofit organization supporting individuals and their families affected by Guillain-Barre’ syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), Multifocal Motor Neuropathy (MMN) and related conditions through a commitment to support, education, research and advocacy. Access valuable information, community, and industry events through the GBS | CIDP Foundation International.

National Organization for Rare Disorders (NORD)
NORD advances practical, meaningful, and enduring change so people with rare diseases can live their fullest and best lives. They offer disease information, community events and programs, and financial assistance programs for individuals with rare diseases, such as CIDP.

IVIG & SCIG Support Community
Founded by CSI Pharmacy, the IVIG & SCIG Support Community on Facebook is a group for individuals and caregivers of adults or children receiving IVIG/SCIG treatments. This community is designed to educate, empower, and support members on their journey. It’s a space for individuals impacted by rare and chronic diseases, including CIDP, to access resources, ask questions, share insights, and more.

Convenient & Effective In-Home IVIg Treatments for CIDP with CSI Pharmacy

CIDP is a rare and complex condition, with the right treatments and support, individuals with CIDP can successfully manage their symptoms and enhance their quality of life. Access to therapies such as in-home IVIg treatments from CSI Pharmacy provides a convenient and effective option for those living with CIDP. If you or a loved one is navigating this condition, consult with the CSI team to explore personalized treatment options and comprehensive support tailored to your needs.

References:
Gogia B, Rocha Cabrero F, Khan Suheb MZ, et al. Chronic Inflammatory Demyelinating Polyradiculoneuropathy. [Updated 2024 Mar 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK563249/

Categories
IG Therapy

Understanding IVIg vs SCIg Infusions

Hands, IV drip and saline solution in hospital, clinic and healthcare facility for health and healing. Doctor, nurse and closeup of medical equipment for intensive care, life support and medicine

Immunoglobulin therapy, also known as Ig therapy, has become an effective treatment for a variety of autoimmune and immune deficiency conditions. Whether you are considering treatment options for yourself or a loved one, understanding the different types of immunoglobulin therapies, IVIg (Intravenous Immunoglobulin) and SCIg (Subcutaneous Immunoglobulin), is important for making an informed decision. We’ll explain the differences between IVIg and SCIg and highlight important points to think about.

What is Immunoglobulin (Ig) Therapy?

Immunoglobulins are proteins that naturally occur in your immune system and are found in donated human plasma. These proteins are antibodies that play a vital role in defending the body against harmful pathogens (germs), such as bacteria and viruses.

Ig therapy involves infusions of healthy immunoglobulins to treat conditions such as primary immunodeficiency, autoimmune diseases, and some neurological disorders.
In some patients, the immune system doesn’t produce enough immunoglobulins (immune deficiency) so the Ig therapy replaces what is missing in the body. At higher doses for auto-immune conditions, Ig therapy helps to regulate the immune system.
Treatment goals may include reducing infections for immune deficiency, and for autoimmune conditions, decreasing the disease symptoms and stopping the disease from getting worse.

Getting to Know IVIg (Intravenous Immunoglobulin)

IVIg is one of the most common forms of Ig therapy. During an IVIg infusion treatment, immunoglobulins are injected directly into the bloodstream through an intravenous (IV) infusion. IVIg infusions are administered by a trained infusion nurse every 3-4 weeks in the comfort of your home or a clinic setting. IVIg infusions can take anywhere from a few hours to several hours, depending on the dose and the patient’s needs.

Getting to Know SCIg (Subcutaneous Immunoglobulin)

SCIg infusion therapy is another type of Ig therapy that’s administered into the fatty tissue under the skin (subcutaneously). SCIg can be administered at home by the patient themselves, after receiving proper training from an experienced infusion nurse. SCIg requires a few needles for each infusion (typically 3-4 needles) and has more frequent administration compared to IVIg. The subcutaneous infusions can be done in smaller doses a few days a week or larger doses once weekly or every other week.

Comparing IVIg & SCIg Infusions

IVIg and SCIg infusions are both potential treatment options for patients with immunodeficiencies, autoimmune diseases, and neurological conditions including:

      • Primary Immunodeficiencies (PID)

      • Myasthenia Gravis (MG)

      • Dermatomyositis

      • Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

      • Multifocal Motor Neuropathy (MMN)

    The main differences between these two administration methods of Immunoglobulin are shown in the table below.

    Factors to Consider

    IVIg Infusion

    SCIg Infusion

    Administration

    		 Intravenous (IV), given by a trained infusion nurse Subcutaneous (under the skin), self-administered after required training

    Frequency of Treatment

    		 Every 3-4 weeks Daily, weekly, or every other week

    Infusion Location

    		 Can be administered by a home infusion nurse or in a clinic setting Can be done at home via self-administration after proper training

    Needle Sticks

    		 1 needle stick per treatment Multiple needle sticks needed depending on the dose

    IVIg vs SCIg: Which Option is Right for You?

    Choosing between IVIg and SCIg depends on several factors, including your specific medical condition, treatment goals, lifestyle, and the recommendations of your healthcare team. Both are effective options for treating a variety of autoimmune and immune deficiency conditions. Consult with your healthcare provider to determine which treatment method is best fit for your needs and treatment goals.

    IVIg & SCIg Home Infusion Therapy with CSI Pharmacy

    At CSI Pharmacy, we specialize in IVIg and SCIg infusion therapies for patients with immunodeficiencies, autoimmune, and other rare or chronic conditions. Our nationwide team of nurses is committed to delivering expert, compassionate care in the comfort of your home. Alongside our dedicated pharmacy, insurance & reimbursement, and intake teams, we ensure that you have the support you need every step of the way. If you’re looking for an IVIg or SCIg partner, let us help make the process seamless and stress-free.