Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a rare neurological disorder that affects the peripheral nervous system, causing progressive weakness, sensory loss, and discomfort. Understanding CIDP, its symptoms, and available treatments essential for patients, caregivers, and healthcare providers. In this article, we’ll share information about CIDP, from diagnosis to treatment options.
What Is CIDP?
CIDP, Chronic Inflammatory Demyelinating Polyneuropathy, is an autoimmune disorder where the body’s immune system attacks the myelin sheaths that covers the nerves in the peripheral nervous system. This leads to muscle weakness, numbness, and difficulty walking. CIDP is often compared to Guillain-Barre syndrome (GBS), but CIDP progresses over a longer period, causing more gradual nerve damage than GBS. According to Cleveland Clinic, researchers estimate that there are 0.8 to 8.9 new cases of CIDP per 100,000 people in the United States each year.
Symptoms of CIDP
CIDP symptoms often vary by person and develop slowly, making detection challenging. Common symptoms of CIDP include:
- Chronically Progressive Muscle Weakness: Muscle strength may gradually diminish over 2 months or longer, particularly in the legs and arms.
- Sensory Disturbances: Individuals affected by CIDP may experience numbness or tingling.
- Fatigue: Constant tiredness can make it difficult to complete daily activities.
- Difficulty with Coordination: Walking and maintaining balance can become challenging for individuals with CIDP.
- Neuropathic Pain: Nerve pain is common and can range from mild discomfort to intense burning or sharp sensations.
Diagnosing CIDP
Healthcare providers will utilize a combination of diagnostic methods to evaluate for CIDP including medical history review, physical exams, and diagnostic tests. Common tests for CIDP include nerve conduction studies, spinal tap (lumbar puncture), and blood tests. Early diagnosis and intervention can help to effectively manage the progression of the disease to improve the patient’s quality of life.
Treatment Options for CIDP
There is currently no cure for CIDP but several treatments help manage the symptoms. The most common treatment options include:
- Corticosteroids: These prescription medications, such as prednisone, can help reduce inflammation.
- Steroid-sparing Immunosuppressants: These prescription medications may include methotrexate, azathioprine, and mycophenolate.
- Intravenous Immunoglobulin (IVIg): This infusion therapy helps regulate the immune system, promote nerve function recovery, and provide symptom relief to slow disease progression.
Resources for Individuals with CIDP & Caregivers
Support and education are important for individuals with CIDP and their caregivers. Several organizations offer valuable resources including education, community support, and even financial assistance. Some helpful organizations for individuals with CIDP include:
GBS | CIDP Foundation International
The GBS | CIDP Foundation International is a global nonprofit organization supporting individuals and their families affected by Guillain-Barre’ syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), Multifocal Motor Neuropathy (MMN) and related conditions through a commitment to support, education, research and advocacy. Access valuable information, community, and industry events through the GBS | CIDP Foundation International.
National Organization for Rare Disorders (NORD)
NORD advances practical, meaningful, and enduring change so people with rare diseases can live their fullest and best lives. They offer disease information, community events and programs, and financial assistance programs for individuals with rare diseases, such as CIDP.
IVIG & SCIG Support Community
Founded by CSI Pharmacy, the IVIG & SCIG Support Community on Facebook is a group for individuals and caregivers of adults or children receiving IVIG/SCIG treatments. This community is designed to educate, empower, and support members on their journey. It’s a space for individuals impacted by rare and chronic diseases, including CIDP, to access resources, ask questions, share insights, and more.
Convenient & Effective In-Home IVIg Treatments for CIDP with CSI Pharmacy
CIDP is a rare and complex condition, with the right treatments and support, individuals with CIDP can successfully manage their symptoms and enhance their quality of life. Access to therapies such as in-home IVIg treatments from CSI Pharmacy provides a convenient and effective option for those living with CIDP. If you or a loved one is navigating this condition, consult with the CSI team to explore personalized treatment options and comprehensive support tailored to your needs.
References:
Gogia B, Rocha Cabrero F, Khan Suheb MZ, et al. Chronic Inflammatory Demyelinating Polyradiculoneuropathy. [Updated 2024 Mar 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK563249/
